An efficient method to detect polymorphism
Researchers Rafael B. León Cachón, María Guadalupe Moreno Treviño, and Denis Aideé Martínez Treviño developed a method to detect GSTM3 A/B polymorphism in Human DNA samples in 2017. Polymorphism is related to the metabolism of drugs and carcinogens; therefore, it is associated with cancer.
Currently, polymorphism detection is carried out mostly through PCR-nucleotide sequencing and RFLPs. However, this requires long processes that can be costly. This innovation consists of designing TaqMan probes specific to the genetic variants and using another method called PCR in real time.